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Astros host the Phillies, try to continue home win streak

Philadelphia Phillies (47-32, first in the NL East) vs. Houston Astros (46-33, first in the AL West) Houston; Wednesday, 8:10 p.m. EDT PITCHING PROBABLES: Phillies: Zack Wheeler (7-2, 2.61 ERA, 0.
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Greene leads Tigers against the Athletics after 4-hit game

Athletics (32-49, fifth in the AL West) vs. Detroit Tigers (50-30, first in the AL Central) Detroit; Wednesday, 6:40 p.m. EDT PITCHING PROBABLES: Athletics: Jacob Lopez (1-4, 4.25 ERA, 1.44 WHIP, 49 strikeouts); Tigers: Jack Flaherty (5-8, 4.
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Brewers and Pirates meet to decide series winner

Pittsburgh Pirates (32-49, fifth in the NL Central) vs. Milwaukee Brewers (44-36, second in the NL Central) Milwaukee; Wednesday, 2:10 p.m. EDT PITCHING PROBABLES: Pirates: Paul Skenes (4-6, 1.85 ERA, 0.
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Orioles and Rangers meet, winner claims 3-game series

Texas Rangers (39-41, fourth in the AL West) vs. Baltimore Orioles (34-45, fifth in the AL East) Baltimore; Wednesday, 6:35 p.m. EDT PITCHING PROBABLES: Rangers: Jacob deGrom (7-2, 2.24 ERA, 0.
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Cubs take 3-game losing streak into matchup with the Cardinals

Chicago Cubs (46-33, first in the NL Central) vs. St. Louis Cardinals (44-36, third in the NL Central) St. Louis; Wednesday, 7:45 p.m. EDT PITCHING PROBABLES: Cubs: Matthew Boyd (6-3, 2.84 ERA, 1.
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Marlins bring road win streak into game against the Giants

Miami Marlins (32-45, fourth in the NL East) vs. San Francisco Giants (44-35, second in the NL West) San Francisco; Wednesday, 9:45 p.m. EDT PITCHING PROBABLES: Marlins: Edward Cabrera (2-2, 3.81 ERA, 1.
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White Sox host the Diamondbacks on home losing streak

Arizona Diamondbacks (41-38, fourth in the NL West) vs. Chicago White Sox (25-55, fifth in the AL Central) Chicago; Wednesday, 2:10 p.m. EDT PITCHING PROBABLES: Diamondbacks: Zac Gallen (5-8, 5.60 ERA, 1.
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Toronto Blue Jays and Cleveland Guardians play in game 2 of series

Toronto Blue Jays (42-36, third in the AL East) vs. Cleveland Guardians (39-38, second in the AL Central) Cleveland; Wednesday, 6:40 p.m. EDT PITCHING PROBABLES: Blue Jays: Max Scherzer (0-0); Guardians: Gavin Williams (5-3, 3.58 ERA, 1.
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Mets to stop slide in matchup with the Braves

Atlanta Braves (37-41, third in the NL East) vs. New York Mets (46-34, second in the NL East) New York; Wednesday, 7:10 p.m. EDT PITCHING PROBABLES: Braves: Didier Fuentes (0-1, 7.20 ERA, 1.40 WHIP, three strikeouts); Mets: Clay Holmes (7-4, 3.
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Dodgers face the Rockies leading series 1-0

Los Angeles Dodgers (49-31, first in the NL West) vs. Colorado Rockies (18-61, fifth in the NL West) Denver; Wednesday, 8:40 p.m. EDT PITCHING PROBABLES: Dodgers: Yoshinobu Yamamoto (6-6, 2.76 ERA, 1.
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